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In some embodiments, the formulations or composition described herein have a pH and osmolarity as described herein, and have a concentration of active pharmaceutical ingredient between about 0.1-about 70 mg/mL, between about 1 mg-about 70 mg/mL, between about 1 mg-about 50 mg/mL, between about 1 mg/mL and about 20 mg/mL, between about 1 mg/mL to about 10 mg/mL, between about 1 mg/mL to about 5 mg/mL, or between about 0.5 mg/mL to about 5 mg/mL of the active agent by volume of the formulation or composition

The difficult part is balance

The thiol group of glutathione chelates copper ions on the active site of enzyme tyrosinase thus inhibiting it

BPC-157 also restored nucleus pulposus cells damaged by inflammation, maintained protective proteins, and improved cell survival